3 files changed, 74 insertions, 0 deletions
diff --git a/tools/facets-app.nix b/tools/facets-app.nix
new file mode 100644
index 0000000..8c4a7b2
--- /dev/null
+++ b/tools/facets-app.nix
@@ -0,0 +1,42 @@
+{buildRPackage
+,fetchFromGitHub
+,R
+,htslib
+,zlib}:
+
+let
+  pctGCdata = buildRPackage rec {
+    name = "pctGCdata-${version}";
+    version = "0.2.0";
+    requireX = false;
+    src = fetchFromGitHub {
+      owner = "mskcc";
+      repo = "pctGCdata";
+      rev = "v${version}";
+      sha256 = "1qq0fmm3zwz6rv0ka82850ww0qj50621gln9i0gfs8k3wyqil4l8";
+    };
+    buildInputs = [ R ];
+  };
+
+in buildRPackage rec{
+  name = "facets-${version}";
+  version = "0.5.6";
+  requireX = false;
+  src = fetchFromGitHub {
+    owner = "mskcc";
+    repo = "facets";
+    rev = "v${version}";
+    sha256 = "0yqr23446y2h8xgbgj0r6sl4i778111drgsi06a2cqy530xcmbxs";
+  };
+  buildInputs = [ R htslib zlib ];
+  propagatedBuildInputs = [ pctGCdata ];
+  postBuild = ''
+    cd inst/extcode
+    g++ --std=c++11 snp-pileup.cpp -lhts -o snp-pileup
+    cd ../../
+  '';
+  postInstall = ''
+    mkdir -p $out/bin
+    cp inst/extcode/snp-pileup $out/bin
+  '';
+}
diff --git a/tools/facets-call.nix b/tools/facets-call.nix
new file mode 100644
index 0000000..021cacc
--- /dev/null
+++ b/tools/facets-call.nix
@@ -0,0 +1,24 @@
+{bionix}:
+
+{vcf, bams}:
+
+with bionix;
+with types;
+with lib;
+
+assert (matchFiletype "facets-call-vcf" { vcf = _: true; } vcf);
+assert (all (matchFiletype "facets-call-bam" { bam = _: true; }) bams);
+assert (all (matchFileSorting "facets-call-bam" { coord = _: true; }) bams);
+
+stage {
+  name = "facets";
+  buildInputs = [ facets.app ];
+  buildCommand = ''
+    # Facets requires lexical sorting on the VCF files
+    grep '^#' ${vcf} > input.vcf
+    grep -v '^#' ${vcf} | LC_ALL=C sort -t $'\t' -k1,1 -k2,2n >> input.vcf || true
+
+    # Now actually run facets
+    snp-pileup input.vcf $out ${concatStringsSep " " bams}
+  '';
+}
diff --git a/tools/facets.nix b/tools/facets.nix
new file mode 100644
index 0000000..ed10ffa
--- /dev/null
+++ b/tools/facets.nix
@@ -0,0 +1,8 @@
+{bionix}:
+
+with bionix;
+
+{
+  app = lib.callPackageWith (pkgs // pkgs.rPackages) ./facets-app.nix {};
+  callCNV = callBionix ./facets-call.nix;
+}