From 8002173b2aa2b0a4e1c0300bb4e2aa0422849e65 Mon Sep 17 00:00:00 2001
From: Justin Bedo <cu@cua0.org>
Date: Tue, 23 Oct 2018 13:59:45 +1100
Subject: Wrap inferCNV

Resolves #8
---
 tools/infercnv-app.nix      | 93 +++++++++++++++++++++++++++++++++++++++++++++
 tools/infercnv-infer.nix    | 24 ++++++++++++
 tools/infercnv-ngchmr.patch | 13 +++++++
 tools/infercnv.nix          |  9 +++++
 4 files changed, 139 insertions(+)
 create mode 100644 tools/infercnv-app.nix
 create mode 100644 tools/infercnv-infer.nix
 create mode 100644 tools/infercnv-ngchmr.patch
 create mode 100644 tools/infercnv.nix

(limited to 'tools')

diff --git a/tools/infercnv-app.nix b/tools/infercnv-app.nix
new file mode 100644
index 0000000..ad6a16f
--- /dev/null
+++ b/tools/infercnv-app.nix
@@ -0,0 +1,93 @@
+{stdenv
+  ,fetchurl
+  ,fetchFromGitHub
+  ,callPackage
+  ,nettools
+  ,rPackages
+  ,rWrapper
+  ,R
+  ,jre
+  ,python
+  ,pythonPackages
+  ,darwin
+  ,gettext
+  ,gfortran
+,makeWrapper}:
+
+let
+  buildRPackage = callPackage "${<nixpkgs>}/pkgs/development/r-modules/generic-builder.nix" {
+    inherit R gettext gfortran;
+    inherit (darwin.apple_sdk.frameworks) Cocoa Foundation;
+  };
+
+  GMD = buildRPackage rec {
+    name = "GMD-${version}";
+    version = "0.3.3";
+    src = fetchurl {
+      url = "https://cran.r-project.org/src/contrib/Archive/GMD/GMD_0.3.3.tar.gz";
+      sha256 = "0jshdcmqcr7lz4p5xb76qbaqavm2609r01lhi9hd0aqnnry18kmg";
+    };
+    buildInputs = with rPackages; [ R gplots ];
+  };
+
+  NGCHMR = buildRPackage rec {
+    name = "NGCHMR-${version}";
+    version = "git";
+    src = fetchFromGitHub {
+      owner = "bmbroom";
+      repo = "NGCHMR";
+      rev = "9f5f1fbf39339d21295b5056e469edcdcbaae142";
+      sha256 = "0paw3fz22kbk4ps4mfxzfchqvipspl7a60jsz46fsg10v6d3z7yv";
+    };
+    propagatedBuildInputs = with rPackages; [ R tsvio digest httr jsonlite nettools ];
+    patches = [ ./infercnv-ngchmr.patch ];
+  };
+
+  tsvio = buildRPackage rec {
+    name = "tsvio-${version}";
+    version = "git";
+    src = fetchFromGitHub {
+      owner = "bmbroom";
+      repo = "tsvio";
+      rev = "067b01ffc1491d50fc1e104b1fe36208a3997980";
+      sha256 = "05byfn2bim51wswffs9lm23p4i0bghyn63rny480dvagydn1a85c";
+    };
+  };
+
+  inferCNV = buildRPackage rec {
+    name = "inferCNV-${version}";
+    version = "git";
+    requireX = false;
+    src = fetchFromGitHub {
+      owner = "broadinstitute";
+      repo = "inferCNV";
+      rev = "cf442af0db6191fa8ba57c4921ac2d1f98c2c39d";
+        sha256 = "0cv8qiaqpd6b4152dplnzvgv77cmk961rmvzr27qgmlaazc5hblh";
+    };
+    propagatedBuildInputs = with rPackages; [ R GMD NGCHMR RColorBrewer gplots optparse logging ];
+  };
+
+  r = rWrapper.override {
+    packages = with rPackages; [ inferCNV ape ];
+  };
+
+  py = python.withPackages (pkgs: with pkgs; [ statistics ]);
+
+  shaidymapgen = fetchurl {
+    url = "http://tcga.ngchm.net/NGCHM/ShaidyMapGen.jar";
+    sha256 = "1pz710ig8nnydz329ry8fydccbrp3arp614dgba3bcyy9flm3gnw";
+  };
+
+in stdenv.mkDerivation rec {
+  name = inferCNV.name;
+  src = inferCNV.src;
+  buildInputs = [ r makeWrapper py ];
+  propagatedBuildInputs = [ jre ];
+  installPhase = ''
+    mkdir -p $out/bin
+    cp scripts/* $out/bin
+  '';
+  postFixup = ''
+    wrapProgram $out/bin/inferCNV.R --set SHAIDYMAPGEN=${shaidymapgen}
+  '';
+}
diff --git a/tools/infercnv-infer.nix b/tools/infercnv-infer.nix
new file mode 100644
index 0000000..95ebbe3
--- /dev/null
+++ b/tools/infercnv-infer.nix
@@ -0,0 +1,24 @@
+{bionix
+,nixpkgs
+,flags ? null}:
+
+with nixpkgs;
+with lib;
+
+{ref
+,expr
+,pos}:
+
+stdenv.mkDerivation {
+  name = "inferCNV";
+  buildInputs = [ bionix.infercnv.app ];
+  buildCommand = ''
+    inferCNV.R --output_dir $TMPDIR \
+      ${optionalString (flags != null) flags} \
+      --ref ${ref} \
+      ${expr} \
+      ${pos}
+    mkdir $out
+    cp -r $TMPDIR/* $out
+  '';
+}
diff --git a/tools/infercnv-ngchmr.patch b/tools/infercnv-ngchmr.patch
new file mode 100644
index 0000000..454cf5d
--- /dev/null
+++ b/tools/infercnv-ngchmr.patch
@@ -0,0 +1,13 @@
+diff --git a/inst/base.config/conf.d/01-server-protocol-scl.R b/inst/base.config/conf.d/01-server-protocol-scl.R
+index 1ae302a..6156fa3 100644
+--- a/inst/base.config/conf.d/01-server-protocol-scl.R
++++ b/inst/base.config/conf.d/01-server-protocol-scl.R
+@@ -3,7 +3,7 @@
+ (function() {
+ 
+     if (Sys.info()[['sysname']] != "Windows")  {
+-        thisHost <- c("localhost", system("/bin/hostname -f", intern=TRUE));
++        thisHost <- c("localhost", system("hostname -f", intern=TRUE));
+     } else {
+         thisHost <- c("localhost", paste(Sys.getenv('COMPUTERNAME'),Sys.getenv('USERDNSDOMAIN'),sep='.'));
+     }
diff --git a/tools/infercnv.nix b/tools/infercnv.nix
new file mode 100644
index 0000000..518ca76
--- /dev/null
+++ b/tools/infercnv.nix
@@ -0,0 +1,9 @@
+{nixpkgs, bionix}:
+
+with nixpkgs;
+with bionix;
+
+{
+  app = callPackage ./infercnv-app.nix {};
+  infercnv = callBionix ./infercnv-infer.nix {};
+}
-- 
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