{ bionix , dbnsfp , heapSize ? "31g" , fields ? [ ] , flags ? "" }: input: with bionix; with lib; with types; assert (matchFiletype "snpeff-dbnsfp" { vcf = _: true; } input); stage { name = "snpeff-dbnsfp"; JAVA_TOOL_OPTIONS = "-Xmx${heapSize}"; buildCommand = '' ln -s ${dbnsfp.db} dbNSFP.txt.gz ln -s ${dbnsfp.index} dbNSFP.txt.gz.tbi snpsift dbnsfp -db dbNSFP.txt.gz ${optionalString (length fields > 0) "-f ${concatStringsSep "," fields}"} ${flags} ${input} > $out ''; buildInputs = with pkgs; [ snpeff ]; passthru.filetype = input.filetype; }