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author | Justin Bedo <cu@cua0.org> | 2017-05-10 16:01:59 +1000 |
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committer | Justin Bedo <cu@cua0.org> | 2017-05-10 16:01:59 +1000 |
commit | f5af7ada6f419382415335f5ae283f8a4643f79c (patch) | |
tree | 42f37945b3b1d0c02aa53d8afa997d5f118ec4a4 | |
parent | 32f0a614798f42d0ff51a325ba183aaa85030b24 (diff) |
-rw-r--r-- | README.md | 10 |
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diff --git a/README.md b/README.md new file mode 100644 index 0000000..63ae7d6 --- /dev/null +++ b/README.md @@ -0,0 +1,10 @@ +# Poission Margin Test + +This is an implementation of the Poission Margin Test (PMT) for +normalisation-free significance analysis of NGS data. Unlike other methods that +have a step to normalise differing library sizes, the PMT incorporates the +library size as part of the model. + +## References + +- Adam Kowalczyk, Justin Bedo, Thomas Conway, and Bryan Beresford-Smith. "The poisson margin test for normalization-free significance analysis of NGS data." Journal of Computational Biology 18.3 (2011): 391-400. |