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diff --git a/README.md b/README.md new file mode 100644 index 0000000..63ae7d6 --- /dev/null +++ b/README.md @@ -0,0 +1,10 @@ +# Poission Margin Test + +This is an implementation of the Poission Margin Test (PMT) for +normalisation-free significance analysis of NGS data. Unlike other methods that +have a step to normalise differing library sizes, the PMT incorporates the +library size as part of the model. + +## References + +- Adam Kowalczyk, Justin Bedo, Thomas Conway, and Bryan Beresford-Smith. "The poisson margin test for normalization-free significance analysis of NGS data." Journal of Computational Biology 18.3 (2011): 391-400. |