From f5af7ada6f419382415335f5ae283f8a4643f79c Mon Sep 17 00:00:00 2001 From: Justin Bedo Date: Wed, 10 May 2017 16:01:59 +1000 Subject: Add README --- README.md | 10 ++++++++++ 1 file changed, 10 insertions(+) create mode 100644 README.md diff --git a/README.md b/README.md new file mode 100644 index 0000000..63ae7d6 --- /dev/null +++ b/README.md @@ -0,0 +1,10 @@ +# Poission Margin Test + +This is an implementation of the Poission Margin Test (PMT) for +normalisation-free significance analysis of NGS data. Unlike other methods that +have a step to normalise differing library sizes, the PMT incorporates the +library size as part of the model. + +## References + +- Adam Kowalczyk, Justin Bedo, Thomas Conway, and Bryan Beresford-Smith. "The poisson margin test for normalization-free significance analysis of NGS data." Journal of Computational Biology 18.3 (2011): 391-400. -- cgit v1.2.3